Protein Formulations for Emulsions and Solid-in-Oil Dispersions
2016; Elsevier BV; Volume: 34; Issue: 6 Linguagem: Inglês
10.1016/j.tibtech.2016.03.001
ISSN0167-9430
AutoresMadalena Martins, Ana Loureiro, Nuno G. Azóia, Carla Silva, Artur Cavaco‐Paulo,
Tópico(s)Lipid Membrane Structure and Behavior
ResumoNeeds from medical and cosmetic areas have led to the design of novel nanosized emulsions and solid-in-oil dispersions of proteins. Here, we describe the production of those emulsions and dispersions using high-energy methodologies such as high-pressure homogenization or ultrasound. Recent work has resulted in new mechanistic insights related to the formation of protein emulsions and dispersions. The production method and composition of these formulations can determine major parameters such as size, stability, and functionality, and therefore their final application. Aqueous nanoemulsions of proteins can be used for drug delivery, while solid-in-oil dispersions are often used in transdermal applications.
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