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Prevalence Of Multiple Sclerosis In The Metropolitan Area Of Edirne City, Turkey

2010; Trakya University; Linguagem: Inglês

10.5174/tutfd.2010.04089.0

1301-3149

Yahya Çelik, Özlem Birgili, Asli Kiyat, Baburhan Güldiken, Hülya Özkan Özdemir, Hakan Yilmaz, Sebahattin Saip, Dilek Kuscu, Nevin Sütlaş, Jale Ağaoğlu, Ufuk Utku, Aksel Sıva,

SARS-CoV-2 and COVID-19 Research

Objective:The prevalence and incidence of multiple sclerosis may vary according to the infl uence of the altitude of a geographical area as well as the genetic and environmental factors.This study ained to determine the incidence and prevalence of multiple sclerosis in Edirne population.Material and Methods: Patients with a defi nite diagnosis of MS according to McDonald's criteria, admitted to one of the three MS clinics in Edirne, were included in this two-stage study.Also the records of hospitals in İstanbul serving patients from Edirne, have been evaluated. Results:The prevalence rate of confi rmed MS patients was 33.9/100000 (95% CI: 32-36) in 2003.The mean annual incidence was 3.48/100000 (95% CI: 2.90-4.00).Mean age of the patients was 36.5±9.6 years.Mean age at onset was 29.2±8.5 years.Mean duration of disease was 6.9±5.2 years.Overall, 69.2% had a relapsing-remitting course, 20.5% had a primary progressive course and 10.3% had a secondary progressive course.Mean Expanded Disability Status Scale score was 3.04±2.18.The prevalence and annual incidence after one year was 36.5 per 100000 (95% CI: 33.2-38.6)and 2.60 per 100000 (95% CI: 2.1-3.8),respectively. Conclusion:This is the fi rst city-based MS prevalence study performed in Turkey.The MS prevalence in Edirne is similar to that of Greece and Bulgaria but lower than that of European countries.