Portal de Periódicos da CAPES

Osteogenesis imperfecta and campomelic dysplasia: difficulties in prenatal diagnosis.

1994; Wiley; Volume: 13; Issue: 9 Linguagem: Inglês

10.7863/jum.1994.13.9.691

1550-9613

R C Sanders, R T Greyson-Fleg, W. Allen Hogge, Karin J. Blakemore, Kathryn D. McGowan, S. Isbister,

Bone fractures and treatments

The classic features of osteogenesis imperfecta and campomelic dysplasia typically are so specific that these two forms of skeletal dysplasia are among the few that can be diagnosed in the second trimester of pregnancy. We report a series of seven examples of osteogenesis imperfecta and one example of campomelic dwarfism to illustrate the difficulty of differentiating these two disorders in utero. The prenatal sonographic findings in three of the osteogenesis imperfecta cases mimicked campomelic dwarfism, whereas the case of campomelic dwarfism was antenatally diagnosed as osteogenesis imperfecta.