Effect of dexamethasone on plasma prolactin and cortisol levels in psychiatric patients
1982; American Psychiatric Association; Volume: 139; Issue: 6 Linguagem: Inglês
10.1176/ajp.139.6.763
ISSN1535-7228
AutoresHerbert Y. Meltzer, V. S. Fang, Betty Jo Tricou, Alan Robertson, S K Piyaka,
Tópico(s)Tryptophan and brain disorders
ResumoBack to table of contents Previous article Next article No AccessEffect of dexamethasone on plasma prolactin and cortisol levels in psychiatric patientsPublished Online:1 Apr 2006https://doi.org/10.1176/ajp.139.6.763AboutSectionsView articleAbstractPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack Citations ShareShare onFacebookTwitterLinked InEmail View articleAbstractIn addition to its ability to decrease plasma cortisol levels, dexamethasone can also significantly decrease plasma prolactin levels. In 52 psychiatric patients, including 26 patients with primary major depression or schizoaffective depression, primarily affective type, there was a significant association between nonsuppression of plasma cortisol and prolactin after administration of dexamethasone. These results suggest that the abnormal cortisol response to dexamethasone in some psychiatric patients may be due to a pituitary gland abnormality rather than to a limbic system abnormality. The sensitivity and specificity of the dexamethasone suppression test for endogenous depression were less than previously reported. Access content To read the fulltext, please use one of the options below to sign in or purchase access. Personal login Institutional Login Sign in via OpenAthens Register for access Purchase Save for later Item saved, go to cart PPV Articles - American Journal of Psychiatry $35.00 Add to cart PPV Articles - American Journal of Psychiatry Checkout Please login/register if you wish to pair your device and check access availability. Not a subscriber? Subscribe Now / Learn More PsychiatryOnline subscription options offer access to the DSM-5 library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development. Need more help? 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FiguresReferencesCited byDetailsCited byAndrologia, Vol. 22, No. 1Psychiatry Research, Vol. 58, No. 1Biological Psychiatry, Vol. 33, No. 10Biological Psychiatry, Vol. 30, No. 10Biological Psychiatry, Vol. 29, No. 11Serum postdexamethasone prolactin measures in depressive patients and control subjectsJournal of Psychiatric Research, Vol. 25, No. 3Journal of Affective Disorders, Vol. 22, No. 1-2British Journal of Psychiatry, Vol. 159, No. 2Prolactin responses in dexamethasone suppression test in patients with anorexia nervosa23 August 2007 | Acta Psychiatrica Scandinavica, Vol. 82, No. 4Variability in the application of contemporary diagnostic criteria: endogenous depression as an example1 April 2006 | American Journal of Psychiatry, Vol. 147, No. 9Aging Clinical and Experimental Research, Vol. 2, No. 2Journal of Affective Disorders, Vol. 19, No. 3European Archives of Psychiatry and Neurological Sciences, Vol. 238, No. 5-6Journal of Neural Transmission, Vol. 75, No. 3Biological Psychiatry, Vol. 25, No. 1Biological Psychiatry, Vol. 25, No. 1Biological Psychiatry, Vol. 25, No. 7Psychiatry Research, Vol. 29, No. 2Comparison of in vivo and in vitro glucocorticoid sensitivity in depression: Relationship to the dexamethasone suppression testBiological Psychiatry, Vol. 24, No. 6Dexamethasone suppression test23 August 2007 | Acta Psychiatrica Scandinavica, Vol. 78, No. S345Prolactin in patients with major depressive disorde and in healthy subjectsBiological Psychiatry, Vol. 24, No. 3Journal of Neural Transmission, Vol. 71, No. 3Measurement of ACTH and prolactin in the Dexamethasone Suppression Test23 August 2007 | Acta Psychiatrica Scandinavica, Vol. 76, No. 5Prolactin response to dexamethasone: A study on normal controls and depressed patients23 August 2007 | Acta Psychiatrica Scandinavica, Vol. 76, No. 2The pitfalls of the dexamethasone suppression test: A biological marker of endogenous depression?13 October 2004 | Human Psychopharmacology: Clinical and Experimental, Vol. 2, No. 2Genetics of Steroid Receptors and Their DisordersPsychoneuroendocrinology, Vol. 12, No. 4Psychoneuroendocrinology, Vol. 12, No. 4Dexamethasone suppression test in schizophrenic patients before and during neuroleptic treatmentActa Psychiatrica Scandinavica, Vol. 74, No. 2The dexamethasone suppression test in depressed and non‐depressed geriatric medical inpatients23 August 2007 | Acta Psychiatrica Scandinavica, Vol. 73, No. 5Cognitive Therapy and Research, Vol. 10, No. 3Biological Psychiatry, Vol. 21, No. 7Psychiatry Research, Vol. 19, No. 1Pain, Vol. 25, No. 1Psychoneuroendocrinology, Vol. 11, No. 3British Journal of Psychiatry, Vol. 148, No. 4Glucocorticoid receptors in depression: relationship to the dexamethasone suppression test1 April 2006 | American Journal of Psychiatry, Vol. 142, No. 11Neuroendocrine Changes in Depression26 June 2016 | Australian & New Zealand Journal of Psychiatry, Vol. 19, No. 2The Diagnostic Distribution of Dexamethasone Non-Suppressors26 June 2016 | Australian & New Zealand Journal of Psychiatry, Vol. 19, No. 2Life Sciences, Vol. 36, No. 26Journal of Affective Disorders, Vol. 8, No. 2Journal of Affective Disorders, Vol. 8, No. 1Psychiatry Research, Vol. 16, No. 2Psychiatry Research, Vol. 14, No. 3Psychiatry Research, Vol. 14, No. 3Behavioral and Brain Sciences, Vol. 8, No. 1Behavioral and Brain Sciences, Vol. 8, No. 1Behavioral and Brain Sciences, Vol. 8, No. 1Behavioral and Brain Sciences, Vol. 8, No. 1Behavioral and Brain Sciences, Vol. 8, No. 1Behavioral and Brain Sciences, Vol. 8, No. 1Behavioral and Brain Sciences, Vol. 8, No. 1Behavioral and Brain Sciences, Vol. 8, No. 1Behavioral and Brain Sciences, Vol. 8, No. 1Behavioral and Brain Sciences, Vol. 8, No. 1Behavioral and Brain Sciences, Vol. 8, No. 1Behavioral and Brain Sciences, Vol. 8, No. 1Behavioral and Brain Sciences, Vol. 8, No. 1Behavioral and Brain Sciences, Vol. 8, No. 1Behavioral and Brain Sciences, Vol. 8, No. 1Behavioral and Brain Sciences, Vol. 8, No. 1Behavioral and Brain Sciences, Vol. 8, No. 1Behavioral and Brain Sciences, Vol. 8, No. 1Behavioral and Brain Sciences, Vol. 8, No. 1Behavioral and Brain Sciences, Vol. 8, No. 1Behavioral and Brain Sciences, Vol. 8, No. 1Behavioral and Brain Sciences, Vol. 8, No. 1Behavioral and Brain Sciences, Vol. 8, No. 1Behavioral and Brain Sciences, Vol. 8, No. 1Behavioral and Brain Sciences, Vol. 8, No. 1Behavioral and Brain Sciences, Vol. 8, No. 1Behavioral and Brain Sciences, Vol. 8, No. 1New England Journal of Medicine, Vol. 312, No. 12Glucocorticoid resistance in depression: the dexamethasone suppression test and lymphocyte sensitivity to dexamethasone1 April 2006 | American Journal of Psychiatry, Vol. 141, No. 11Methodological Standards in Studies Evaluating the Dexamethasone Suppression Test26 June 2016 | Australian & New Zealand Journal of Psychiatry, Vol. 18, No. 3Postdexamethasone prolactin and cortisol: a biological state variable in depression23 August 2007 | Acta Psychiatrica Scandinavica, Vol. 70, No. 3Prolactin response to morphine in depressionPsychiatry Research, Vol. 11, No. 4The dexamethasone suppression test in adolescent psychiatric patients1 April 2006 | American Journal of Psychiatry, Vol. 141, No. 3Journal of Psychiatric Research, Vol. 18, No. 3Psychiatry Research, Vol. 11, No. 1Journal of the American Academy of Child Psychiatry, Vol. 23, No. 4British Journal of Psychiatry, Vol. 145, No. 6Ist der Dexamethason-Suppressionstest ein brauchbares Instrument für die psychiatrische Differentialdiagnostik?Cortisol Secretion and DST in Affective Disorders — Methodological Concerns1 December 1983 | The Canadian Journal of Psychiatry, Vol. 28, No. 8The Joint Mature Women's Clinic or Menopause Revisited1 December 1983 | The Canadian Journal of Psychiatry, Vol. 28, No. 8Dexamethasone suppression test in a pluri‐diagnostic approach: its relationship to psychopathological and clinical variables23 August 2007 | Acta Psychiatrica Scandinavica, Vol. 68, No. 1Psychiatry Research, Vol. 10, No. 3Psychiatry Research, Vol. 8, No. 3Journal of Steroid Biochemistry, Vol. 19, No. 1 Volume 139Issue 6 June 1982Pages 763-768 Metrics PDF download History Published online 1 April 2006 Published in print 1 June 1982
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