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Comparison of PET measurement of local brain glucose metabolism and CAT measurement of brain atrophy in chronic schizophrenia and depression

1986; American Psychiatric Association; Volume: 143; Issue: 2 Linguagem: Inglês

10.1176/ajp.143.2.175

1535-7228

A. Kling, E. Jeffrey Metter, Walter H. Riege, Dietmar Kuhl,

Advanced MRI Techniques and Applications

Back to table of contents Previous article Next article No AccessComparison of PET measurement of local brain glucose metabolism and CAT measurement of brain atrophy in chronic schizophrenia and depressionPublished Online:1 Apr 2006https://doi.org/10.1176/ajp.143.2.175AboutSectionsView articleAbstractPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack Citations ShareShare onFacebookTwitterLinked InEmail View articleAbstractUsing [18F]fluorodeoxyglucose and positron emission tomography (PET), the authors examined the regional brain glucose metabolism of six patients with chronic schizophrenia, six patients with chronic depression, and 12 normal control subjects. Three schizophrenic and four depressive patients had CAT scans that showed enlarged ventricles (ventricle-brain ratios higher than 9.0) and widened sylvian fissures. The PET scans of the schizophrenic and depressed patients did not differ significantly from those of the age-matched controls, and a previously reported metabolic "hypofrontality" was not confirmed. The patients with enlarged ventricles and widened sylvian fissures tended to have lower global metabolism. Access content To read the fulltext, please use one of the options below to sign in or purchase access. Personal login Institutional Login Sign in via OpenAthens Purchase Save for later Item saved, go to cart PPV Articles - American Journal of Psychiatry $35.00 Add to cart PPV Articles - American Journal of Psychiatry Checkout Please login/register if you wish to pair your device and check access availability. Not a subscriber? Subscribe Now / Learn More PsychiatryOnline subscription options offer access to the DSM-5 library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development. Need more help? PsychiatryOnline Customer Service may be reached by emailing [email protected] or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.). FiguresReferencesCited byDetailsCited byInternational Journal of Mental Health and Addiction, Vol. 14, No. 4Expert Opinion on Pharmacotherapy, Vol. 15, No. 3PLoS ONE, Vol. 8, No. 4Expert Opinion on Investigational Drugs, Vol. 22, No. 7NeuroImage, Vol. 59, No. 1Neurochemistry International, Vol. 55, No. 7Progress in Neuro-Psychopharmacology and Biological Psychiatry, Vol. 32, No. 2Psychiatry Research: Neuroimaging, Vol. 154, No. 1Journal of Neural Transmission, Vol. 113, No. 7Effects of Psychotic State and Task Demand on Prefrontal Function in Schizophrenia: An fMRI Study of Overt Verbal FluencyCynthia H.Y. 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