Comportamiento del cáncer de pulmón células pequeñas en el hospital "Hermanos Ameijeiras"
2016; Universidad de Ciencias Médicas de Las Tunas; Volume: 41; Issue: 2 Linguagem: Inglês
ISSN
1029-3027
AutoresHaslen Hassiul Cáceres Lavernia, Elia Nenínger Vinageras,
Tópico(s)Neuroendocrine Tumor Research Advances
ResumoBackground : small cell lung carcinoma is approximately in a 15 % of bronchogenic carcinomas. At diagnosis, between 70 and 80 % of patients often show the disease disseminated, so most of the patients die, even with the best treatment available. Objective : to describe the behavior of small cell lung carcinoma in patients registered in Hermanos Ameijeiras hospital in Havana during the years 2010 to 2013. Methods : a descriptive and retrospective study was carried out in patients diagnosed with small cell lung cancer treated at the oncology department of that hospital from January, 2010 to December, 2013. The universe of study consisted of 1013 patients diagnosed with lung cancer and the sample comprised 104 patients diagnosed with small cell lung carcinoma. Results : the frequency of small cell lung carcinoma was of a 10,3 % and the predominant age group was 60 to 69 years and in males. The 50 % showed some associated co-morbidity, being hypertension the most frequent one, followed by diabetes mellitus and ischemic heart disease. As the primary site, the right lung prevailed, diagnosed mostly in stage IV, being the liver the most common site of metastasis, followed by the contralateral lung and pleura. The most used treatment was chemotherapy as a single modality or with radiation therapy, reaching a median survival of 7 months. Conclusions : small-cell lung carcinoma is the less frequent histological variant; most of the patients had the disease disseminated at diagnosis. Chemotherapy improves survival but it is curative in only a minority of patients.
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