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Clinical and Biochemical Abnormalities in People Heterozygous for Hemochromatosis

1996; Massachusetts Medical Society; Volume: 335; Issue: 24 Linguagem: Inglês

10.1056/nejm199612123352403

1533-4406

Zaneta J. Bulaj, Linda M. Griffen, Lynn B. Jorde, Corwin Q. Edwards, James P. Kushner,

Folate and B Vitamins Research

Ten percent of whites are heterozygous for the HLA-linked hemochromatosis mutation. We performed a cross-sectional analysis of 1058 genotyped heterozygotes to define the effects of age and sex on the phenotype.