Artigo Revisado por pares

Serotonin in Obsessive Compulsive Disorder

1990; Slack Incorporated (United States); Volume: 20; Issue: 10 Linguagem: Inglês

10.3928/0048-5713-19901001-06

ISSN

1938-2456

Autores

Thomas R. Insel,

Tópico(s)

Neurotransmitter Receptor Influence on Behavior

Resumo

Serotonin in Psychiatric DisordersSerotonin in Obsessive Compulsive Disorder Thomas R Insel, MD, , MD Thomas R Insel, MD Psychiatric Annals, 2013;20(10):560–564Published Online:October 01, 1990https://doi.org/10.3928/0048-5713-19901001-06Cited by:6View Full TextPDF ToolsAdd to favoritesDownload CitationsTrack Citations ShareShare onFacebookTwitterLinkedInRedditEmail SectionsMore1. Insel TR, Zollar J. Psychophainiacologic approaches in obsessive-compulsive disorder. In: Metzer II. eel. Psychophammcology: the Third Generation of Progress. New York, NV: Raven Press Pubs; 1987:12051209. Google Scholar2. Murphy DL. ZoharJ, Benkelfal C. Paio MT, Pigoli TA. Insel TR. Obsessivecompulsive disorder as a 5-HT subsystem-related behavioral disorder. Rr J Psychiatry. 1989; 155:15-24. Google Scholar3. Thoren P. Asberg VI. Bertilsson L, MeIIstrom B, Sjoqvist F, Traskman I.. Clomipramine treatment of obsessive-compulsive disorder, if: biochemical aspects. Arch Cm Psychiatry. 1980; 37:1289-1294. Google Scholar4. Zohar J. Insel TR. Obsessive-compulsive disorder: psychobiological approaches to diagnosis, treatment, and pathophysiology. Biol Psychiatry. 1987; 22:667-687. Google Scholar5. Volavka J, Ncziroglu F, Yaryaru-Tobias JA. Clomipramine and Imipramine in obsessive-compulsive disorder. Psychiatry Res. 1985; 14:83-91. Google Scholar6. Foa EB. Steketee G, Kozak MJ. Dugger I). Effects of Imipramine on depression and obsessive-compvilsive symptoms. Psichiatri Ra. t987;21:L23-126. Google Scholar7. Ananih J, PecknoldJC, van den Steen N. Engelsmann F. Double-blind comparative study of clomipramine and amiti iptyline in obsessive neurosis. Prog Neurapsychopharmacol Biol Psychiatry. 1981;5:257-262. Google Scholar8. Thoren P, Asberg M. Cronholm B, Jornestedt !.. Traskman L. Clomipramine treatment of obsessive-compulsive disorder, I: a controlled clinical trial. Arch Gen Psychiatry. 1 980; 37: 1 28 1 - 1 285. Google Scholar9. Rament MF, Rapopori JL, Murphy DL, Berg CJ. Lake CR. Biochemical changes during clomipramine treatment of childhood obsessive-compulsive disorder. Arch Gen Psychiatry. 1987: 4-1:219-225. Google Scholar10 Benkelfat C, Murphy DL. Zohar J, Hill JL. Gover G. Insel. IR. Clomipramine in obsessive-compulsive disorder: further evidence for a serotonergic mechanism of action. Arch Gen Psichiatri. 1 989: 1 28. Google Scholar11. Zohar J. Mueller EA. Insel TR, ZoharKadouch RC. Murphy UL. Serotonergic responsiviiv in obsessive-compulsive disorder: comparison of patienis healthy controls. Arch Gen Psychiatry. 1987: 44:946-951. Google Scholar12. Insel TR, Mueller EA, Akerman I. Linnoila M. Murphy DL. Obsessive-computsive disorder and serotonin: is there a connection? Biol Psychiatry. 1985; 20:1174-1189. Google Scholar13, Weizman A, Carni) M. Hermesh J). ei al. High-affinity imipramine binding serotonin uptake in platelets of eight adolescent and ten adult obsessivecompulsive patients. Am J Psychiatry. 1986: 143:335-339. Google Scholar14. 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Psychiatry Res. 1988: 25:101-101. Google Scholar19. Gorman JM, Liebowitz MR, Ever AJ, Davies SO, Klein DF1 Lattale infusions in obsessive-compulsive disorder. Am J Psychiatry. 1 985; 142:864-866. Google Scholar20. Rasmussen SA, Goodman WK, Woods SW, Heninger GR, Charney DS. Effects of yohimbine in obsessive-compulsive disorder. Psychopharmacology (Berlin I. 1987;93:308-313. Google Scholar21. Hewletl WA, Vinogradov S. Bennati S, Csernansky J. Agias WS. Fenfluramine stimulation of prolactin release in obsessive-compulsive disorder. Presented at New York Academy of Sciences, The Neuropharmacology ol Serotonin Conference; July 12, 1989: New York. NY Google Scholar22. Hollandei E. DeCaria C. ( UiIIv B, Niles, it A. Liebowitz MR. Serotonergic challenges in obsessive-compulsive disorder. Presen led at New York Academy of Scient es. The Neuropharmacology of Serotonin Conici enee: |iilv 12. 1989; New York, NY Google Scholar23. Baxter LR. Phelps ME, Mazziotta JC, Guze BH, Schwartz JM, Selin CE. I oral cerebral glucose metabolic rales in obsessive compulsive disorder: a comparison with rates in unipolar depression and normal controls. Arch Gen Psychiatry. 1987:44:211-2/8. Google Scholar24. Soubiié P. Reconciling the role of cenlral serotonin neurons in human and animal behavior. Behavioral Brain Sciences. 1986:9:319-364. Google Scholar Previous article Next article FiguresReferencesRelatedDetailsCited by Marais L, Daniels W, Brand L, Viljoen F, Hugo C and Stein D (2006) Psychopharmacology of maternal separation anxiety in vervet monkeys, Metabolic Brain Disease, 10.1007/s11011-006-9011-8, 21:2-3, (191-200), Online publication date: 21-Oct-2006. Fitzgerald K, MacMaster F, Paulson L and Rosenberg D (1999) Neurobiology of Childhood Obsessive-Compulsive Disorder, Child and Adolescent Psychiatric Clinics of North America, 10.1016/S1056-4993(18)30168-8, 8:3, (533-575), Online publication date: 1-Jul-1999. Clarke A, Hedeker D, Ebert M, Schmidt D, McKinney W and Kraemer G (1996) Rearing experience and biogenic amine activity in infant rhesus monkeys, Biological Psychiatry, 10.1016/0006-3223(95)00663-X, 40:5, (338-352), Online publication date: 1-Sep-1996. Franzblau S, Kanadanian M and Rettig E (1995) Critique of reductionistic models of obsessive-compulsive disorder: Toward a new explanatory paradigm, Social Science & Medicine, 10.1016/0277-9536(94)00301-9, 41:1, (99-112), Online publication date: 1-Jul-1995. ALARCON R, JOHNSON B and LUCAS J (1991) Paranoid and Aggressive Behavior in Two Obsessive-Compulsive Adolescents Treated with Clomipramine, Journal of the American Academy of Child & Adolescent Psychiatry, 10.1097/00004583-199111000-00020, 30:6, (999-1002), Online publication date: 1-Nov-1991. BERNSTEIN G and BORCHARDT C (1991) Anxiety Disorders of Childhood and Adolescence: A Critical Review, Journal of the American Academy of Child & Adolescent Psychiatry, 10.1097/00004583-199107000-00001, 30:4, (519-532), Online publication date: 1-Jul-1991. Request Permissions InformationCopyright 2013, SLACK IncorporatedPDF download • 5.4 MB Published online10/01/90

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