Flavonoids Derivatives from Arundina graminifolia and Their Cytotoxicity
2013; ASIAN PUBLICATION CORPORATION; Volume: 25; Issue: 15 Linguagem: Inglês
10.14233/ajchem.2013.14743a
ISSN0975-427X
AutoresLi‐Dan Shu, Yanqiong Shen, Liying Yang, Xuemei Gao, Qiu-Fen Hu,
Tópico(s)Biological and pharmacological studies of plants
ResumoA new flavonoid, 3(S),4(S)-3',4'-dihydroxyl-7,8,-methylenedioxylpterocarpan (1), together with ten known flavonoids derivatives (2-11), were isolated from the whole plant of Arundina gramnifolia.The structure of compounds 1-11 were elucidated by spectroscopic methods including extensive 1D and 2D NMR techniques.Compound 1 was also evaluated for its cytotoxicity against five human tumor cell lines.The results revealed that compound 1 showed high cytotoxicity against HSY5Y cell with IC50 values of 2.2 µM and moderate cytotoxicities with IC50 valves 5-10 µM for other four tested cell lines.
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