Produção Nacional
Revisado por pares
Combined Training Reduces Subclinical Inflammation in Obese Middle-Age Men
2015; Lippincott Williams & Wilkins; Volume: 47; Issue: 10 Linguagem: Inglês
10.1249/mss.0000000000000658
ISSN1530-0315
AutoresDiego Trevisan Brunelli, Mara Patrícia Traina Chacon‐Mikahil, Arthur Fernandes Gáspari, Wendell Arthur Lopes, Valéria Bonganha, Ivan Luiz Padilha Bonfante, Maria Luisa Bellotto, Cleiton Augusto Libardi, Cláudia Regina Cavaglieri,
Tópico(s)Adipose Tissue and Metabolism
ResumoPurpose We investigated the effects of 24 wk of combined training on proinflammatory and anti-inflammatory markers associated with obesity in obese middle-age men. Methods Thirty obese men (48.73 ± 1.04 yr; body mass index, 31.00 ± 0.29 kg·m−2) underwent 24 wk of combined training [CT (N = 17), aerobic (50%–85% of V˙O2peak) and resistance (6–10 maximum repetition [RM]) training)] three times per week, 60 min per session, or a control group (N = 13). Anthropometric measures, maximal strength for leg press and bench press, peak oxygen uptake (V˙O2peak) and serum concentrations of C-reactive protein (CRP), tumor necrosis factor α (TNF-α), interleukin-6 (IL-6), IL-10, IL-15, resistin, leptin, and adiponectin were determined before (M1) and after 8 (M2), 16 (M3), and 24 (M4) wk of the experimental design. Results Significant increases were observed in the maximal strength for bench press and leg press, V˙O2peak, and serum concentrations of adiponectin and IL-15 for CT. Concomitantly, significant decreases were observed in percentage body fat and serum concentrations of CRP, resistin, and leptin for CT after the experimental period. Conclusion Twenty-four weeks of moderate- to high-intensity CT reduced markers of subclinical inflammation associated with obesity and improved insulin resistance and functional capabilities of obese middle-age men, regardless of dietary intervention and weight loss.
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