Carta Acesso aberto Revisado por pares

Mastic Gum Kills Helicobacter pylori

1998; Massachusetts Medical Society; Volume: 339; Issue: 26 Linguagem: Inglês

10.1056/nejm199812243392618

ISSN

1533-4406

Autores

Farhad Huwez, D Thirlwell, Alan Cockayne, Dlawer A. A. Ala’Aldeen,

Tópico(s)

Helicobacter pylori-related gastroenterology studies

Resumo

To the Editor: Even low doses of mastic gum — 1 mg per day for two weeks — can cure peptic ulcers very rapidly, but the mechanism responsible has not been clear. We have found that mastic is active against Helicobacter pylori, which could explain its therapeutic effect in patients with peptic ulcers. Mastic is a resinous exudate obtained from the stem and the main leaves of Pistacia lentiscus. It is used as a food ingredient in the Mediterranean region. Clinically, mastic has been effective in the treatment of benign gastric ulcers1 and duodenal ulcers.2 In rats, mastic showed cytoprotective . . .

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