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Effect of Methylene Blue on glutamate and reduced glutathione of rabbit erythrocytes

1977; Portland Press; Volume: 168; Issue: 3 Linguagem: Inglês

10.1042/bj1680587

1470-8728

Joy Smith, Edward A. Mahaffey, M Lee,

Advanced Chemical Sensor Technologies

Methylene Blue injected into rabbits resulted in increased glutamate, reduced glutathione and pyrrolid-2-one-5-carboxylate in erythrocytes. The increase in reduced glutathione was probably due to increased glutamate changing the feedback control of glutathione on gamma-glutamylcysteine synthetase.