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Artigo Acesso aberto Revisado por pares
BIBTEX RIS

Long-Term Effects of Indomethacin Prophylaxis in Extremely-Low-Birth-Weight Infants

2001; Massachusetts Medical Society; Volume: 344; Issue: 26 Linguagem: Inglês

10.1056/nejm200106283442602

ISSN

1533-4406

Autores

Barbara Schmidt, Peter G. Davis, Diane Moddemann, Arne Ohlsson, Robin S. Roberts, Saroj Saigal, Alfonso Solimano, Michael Vincer, Linda L. Wright,

Tópico(s)

Infant Development and Preterm Care

Resumo

The prophylactic administration of indomethacin reduces the frequency of patent ductus arteriosus and severe intraventricular hemorrhage in very-low-birth-weight infants (those with birth weights below 1500 g). Whether prophylaxis with indomethacin confers any long-term benefits that outweigh the risks of drug-induced reductions in renal, intestinal, and cerebral blood flow is not known.

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