Artigo Acesso aberto Revisado por pares

Encapsulation of Phthalocyanine Supramolecular Stacks into Virus-like Particles

2011; American Chemical Society; Volume: 133; Issue: 18 Linguagem: Inglês

10.1021/ja110752u

ISSN

1943-2984

Autores

Melanie Brasch, Andrés de la Escosura, Yujie Ma, Charlotte Uetrecht, Albert J. R. Heck, Tomás Torres⊗, Jeroen J. L. M. Cornelissen,

Tópico(s)

Luminescence and Fluorescent Materials

Resumo

We report herein the encapsulation of a water-soluble phthalocyanine (Pc) into virus-like particles (VLPs) of two different sizes, depending on the conditions. At neutral pH, the cooperative encapsulation/templated assembly of the particles induces the formation of Pc stacks instead of Pc dimers, due to an increased confinement concentration. The Pc-containing VLPs may potentially be used as photosensitizer/vehicle systems for biomedical applications such as photodynamic therapy.

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