Produção Nacional
Potentially malignant oral lesions: clinicopathological correlations
2016; Instituto Israelita de Ensino e Pesquisa Albert Einstein; Volume: 14; Issue: 1 Linguagem: Inglês
10.1590/s1679-45082016ao3578
ISSN2317-6385
AutoresHaline Cunha de Medeiros Maia, Najara Alcântara Sampaio Pinto, Joabe dos Santos Pereira, Ana Miryam Costa de Medeiros, Éricka Janine Dantas da Silveira, Márcia Cristina da Costa Miguel,
Tópico(s)Cancer and Skin Lesions
ResumoTo determine the incidence of potentially malignant oral lesions, and evaluate and correlate their clinical and pathological aspects.The sample consisted of cases clinically diagnosed as oral leukoplakia, oral erythroplakia, erythroleukoplakia, actinic cheilitis, and oral lichen planus treated at a diagnostic center, between May 2012 and July 2013. Statistical tests were conducted adopting a significance level of 5% (p≤0.05).Out of 340 patients, 106 (31.2%) had potentially malignant oral lesions; and 61 of these (17.9%) were submitted to biopsy. Actinic cheilitis was the most frequent lesion (37.5%) and the lower lip was the most affected site (49.6%). Among 106 patients in the sample, 48 (45.3%) reported nicotine consumption, 35 (33%) reported alcohol intake and 34 (32.1%) sun exposure while working. When clinical and histopathological diagnoses were compared, oral erythroplakia and atypical ulcer were the lesions that exhibited greater compatibility (100% each).In most cases, clinical and histopathological diagnoses were compatible. An association between the occurrence of erythroplakia, leukoplakia and erythroleukoplakia with smoking was observed. Similarly, an association between actinic cheilitis and sun exposure was noted. Erythroleukoplakia presented the highest malignancy grade in this study. Finally, dental surgeons should draw special attention to diagnosis of potentially malignant oral lesions, choose the best management, and control the lesions to avoid their malignant transformation.
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