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BIBTEX RIS

Mechanisms for the Initiation of Bacteriophage T7 DNA Replication

1983; Cold Spring Harbor Laboratory Press; Volume: 47; Linguagem: Inglês

10.1101/sqb.1983.047.01.078

ISSN

1943-4456

Autores

Carl W. Fuller, Benjamin Beauchamp, Michael Engler, R L Lechner, Steven W. Matson, Stanley Tabor, John H. White, C C Richardson,

Tópico(s)

DNA and Nucleic Acid Chemistry

Resumo

Bacteriophage T7 has developed an efficient and rapid mechanism for the replication of its chromosome. Using this relatively simple organism, it is possible to elucidate the molecular and enzymatic mechanisms responsible for the replication of a linear, duplex DNA molecule (Richardson et al. 1979; Tamanoi et al. 1980b; Tabor et al. 1981). Furthermore, many steps in the replication of the T7 DNA molecule resemble events known to occur during the replication of the larger, more complex bacterial and eukaryotic chromosomes.

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