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MP01-05 GENDER-RELATED DIFFERENCES IN UROTHELIAL CARCINOMA OF THE BLADDER: A POPULATION-BASED STUDY FROM THE SWEDISH NATIONAL REGISTRY OF URINARY BLADDER CANCER

2016; Lippincott Williams & Wilkins; Volume: 195; Issue: 4S Linguagem: Inglês

10.1016/j.juro.2016.02.1835

1527-3792

Andreas Thorstenson, Oskar Hagberg, Börje Ljungberg, Fredrik Liedberg, Georg Jancke, Sten Holmäng, Per‐Uno Malmström, Abolfazl Hosseini, Staffan Jahnson,

Urinary and Genital Oncology Studies

You have accessJournal of UrologyBladder Cancer: Epidemiology & Evaluation I1 Apr 2016MP01-05 GENDER-RELATED DIFFERENCES IN UROTHELIAL CARCINOMA OF THE BLADDER: A POPULATION-BASED STUDY FROM THE SWEDISH NATIONAL REGISTRY OF URINARY BLADDER CANCER Andreas Thorstenson, Oskar Hagberg, Börje Ljungberg, Fredrik Liedberg, Georg Jancke, Sten Holmäng, Per-Uno Malmström, Abolfazl Hosseini, and Staffan Jahnson Andreas ThorstensonAndreas Thorstenson More articles by this author , Oskar HagbergOskar Hagberg More articles by this author , Börje LjungbergBörje Ljungberg More articles by this author , Fredrik LiedbergFredrik Liedberg More articles by this author , Georg JanckeGeorg Jancke More articles by this author , Sten HolmängSten Holmäng More articles by this author , Per-Uno MalmströmPer-Uno Malmström More articles by this author , Abolfazl HosseiniAbolfazl Hosseini More articles by this author , and Staffan JahnsonStaffan Jahnson More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2016.02.1835AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES In modern society, it is assumed that men and women have the same access to cancer treatments. However, there are indications that more aggressive treatment for muscle-invasive urinary bladder cancer is given to men than to women in Sweden. The aim of this investigation was to describe tumor characteristics, treatments, and survival in patients with urinary bladder cancer (UBC) in a national population-based cohort, with special reference to gender-related differences. METHODS All primary UBC patients with urothelial pathology reported to the Swedish National Registry of Urinary Bladder Cancer (SNRUBC) from 1997 to 2011 were included in the study. The SNRUBC has a coverage rate of more than 95% of all Swedish patients with UBC. Women were compared to men regarding TNM classification, primary treatment, and survival. RESULTS In all, 30310 patients (74.9% male, 25.1% female) were entered in the SNRUBC during the indicated period. A larger proportion of women than men had stage T2 to T4, (p < 0.001), and women also had more G1 tumors (p < 0.001). However, compared to women, a larger proportion of men with carcinoma in situ (CIS) or T1G3 received intravesical treatment with BCG or intravesical chemotherapy, and a larger proportion of men with stage T2 to T4 underwent radical cystectomy (37.6% men vs 32.6% women, p < 0.0001). The cancer-specific survival at 5 years was 76.9% for men and 71.5% for women (p < 0.001), and the relative survival at 5 years was 72.3% for men and 69.3% for women (p < 0.001). CONCLUSIONS In this population-based cohort comprising virtually all patients diagnosed with UBC in Sweden between 1997 and 2011, female gender was associated with inferior cancer-specific and relative survival. Although women had a higher rate of aggressive tumours, a smaller proportion of women than men received optimal treatment. © 2016FiguresReferencesRelatedDetails Volume 195Issue 4SApril 2016Page: e2-e3 Advertisement Copyright & Permissions© 2016MetricsAuthor Information Andreas Thorstenson More articles by this author Oskar Hagberg More articles by this author Börje Ljungberg More articles by this author Fredrik Liedberg More articles by this author Georg Jancke More articles by this author Sten Holmäng More articles by this author Per-Uno Malmström More articles by this author Abolfazl Hosseini More articles by this author Staffan Jahnson More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...