Portal de Periódicos da CAPES

Catalytic Hydrogenation of Esters. Development of an Efficient Catalyst and Processes for Synthesising ( R )-1,2-Propanediol and 2-( l -Menthoxy)ethanol

2011; American Chemical Society; Volume: 16; Issue: 1 Linguagem: Inglês

10.1021/op200234j

1520-586X

Wataru Kuriyama, T. MATSUMOTO, Osamu Ogata, Yasunori Ino, Kunimori Aoki, Shigeru Tanaka, Kenya Ishida, Tohru Kobayashi, Noboru Sayo, Takao Saito,

Catalysts for Methane Reforming

A ruthenium catalyst for the reduction of esters by hydrogenation has been developed. Processes for the hydrogenation of esters have also been developed for (R)-1,2-propanediol and 2-(l-menthoxy)ethanol. The catalyst shows good catalytic activity for the hydrogenation of esters in methanol. Methyl lactate was reduced at 30 °C and gave turnover numbers (TON) up to 4000. The optical purity of the (R)-1,2-propanediol made by the hydrogenation of methyl (R)-lactate was higher than that via the asymmetric hydrogenation of hydroxyacetone. A hydrogenation process to replace the lithium aluminum hydride (LAH) reduction used in the production of 2-(l-menthoxy)ethanol was developed.