Artigo Acesso aberto Revisado por pares

Rapid Flow Cytometry Test for Identification of Different Carbapenemases in Enterobacteriaceae

2016; American Society for Microbiology; Volume: 60; Issue: 6 Linguagem: Inglês

10.1128/aac.02947-15

ISSN

1098-6596

Autores

Ana P. Silva, Isabel Faria‐Ramos, Elisabete Ricardo, Isabel M. Miranda, Maria José Espinar, Sofia Costa‐de‐Oliveira, Rafael Cantón, Acácio G. Rodrigues, Cidália Pina‐Vaz,

Tópico(s)

Vibrio bacteria research studies

Resumo

A flow cytometry test was developed to identify carbapenemase production by Enterobacteriaceae and to discriminate between the different types of carbapenemases (classes A, B, and D). It is based on the detection of meropenem activity against bacteria, coupled with different carbapenemase inhibitors, which is assessed by flow cytometry. It represents a convenient, fast, and reliable approach (100% sensitivity and 100% specificity) for the detection and characterization of different carbapenemases.

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