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Freeze tolerance in the frog,Rana sylvatica

1984; Birkhäuser; Volume: 40; Issue: 11 Linguagem: Inglês

10.1007/bf01946664

0014-4754

Kenneth B. Storey,

thermodynamics and calorimetric analyses

Wood frogs survive extracellular freezing at moderate subzero temperatures (−4°C) for at least 11 days. Freezing survival is aided by the accumulation of high concentrations of glucose as a cryoprotectant in blood and tissues. Glucose production was accompanied by a rapid decline in liver, but not muscle, glycogen levels suggesting that liver is the organ controlling cryoprotectant synthesis.