First description of an olfactory neuroblastoma in goldfish Carassius auratus: a case report
2011; Inter-Research; Volume: 96; Issue: 1 Linguagem: Inglês
10.3354/dao02383
ISSN1616-1580
AutoresFabricio Andrés Vigliano, AJ Marcaccini, Javier Sarradell, Roberto Bermúdez, Marı́a Isabel Quiroga,
Tópico(s)Myxozoan Parasites in Aquatic Species
ResumoDAO Diseases of Aquatic Organisms Contact the journal Facebook Twitter RSS Mailing List Subscribe to our mailing list via Mailchimp HomeLatest VolumeAbout the JournalEditorsSpecials DAO 96:61-68 (2011) - DOI: https://doi.org/10.3354/dao02383 First description of an olfactory neuroblastoma in goldfish Carassius auratus: a case report F. A. Vigliano1,2,*, A. J. Marcaccini1, J. Sarradell3, R. Bermúdez4, M. I. Quiroga5 1Cátedra de Histología y Embriología, 2Cátedra de Piscicultura, and 3Cátedra de Patología General y Especial, Facultad de Ciencias Veterinarias, Universidad Nacional de Rosario, S2170HGJ Casilda, Argentina 4Departamento de Anatomía y Producción Animal, and 5Departamento de Ciencias Clínicas Veterinarias, Facultad de Veterinaria, Universidad de Santiago de Compostela, 27002 Lugo, Spain *Email: fviglian@fveter.unr.edu.ar ABSTRACT: An external pinkish growing mass that emerged from the right nostril of an adult goldfish Carassius auratus L. was evaluated by means of light microscopy and immunohistochemistry. The neoplasm presented a well-developed fibrovascular stroma associated with solid cell nests and a large number of Flexner-Wintersteiner rosettes. Myelinated fibres were observed around them. Neoplastic cells showed a prominent degree of nuclear atypia and low mitotic activity. The latter was in agreement with the low reactivity of tumour cells to anti-proliferating cell nuclear antigen antibody. Immunohistochemistry also revealed anti-neuronal nitric oxide synthase, anti-S100 protein, anti-neuropeptide Y, and anti-cytokeratin immunoreactivity in tumour cells as well as in normal olfactory epithelium of goldfish control sections. Histopathological and immunohistochemical findings strongly suggest a diagnosis of an olfactory neuroblastoma (ONB). To our knowledge this is the first description of ONB in goldfish. KEY WORDS: Tumour · Olfactory neuroblastoma · Goldfish · Carassius auratus · Histopathology · Immunohistochemistry Full text in pdf format PreviousNextCite this article as: Vigliano FA, Marcaccini AJ, Sarradell J, Bermúdez R, Quiroga MI (2011) First description of an olfactory neuroblastoma in goldfish Carassius auratus: a case report. Dis Aquat Org 96:61-68. https://doi.org/10.3354/dao02383 Export citation RSS - Facebook - Tweet - linkedIn Cited by Published in DAO Vol. 96, No. 1. Online publication date: August 29, 2011 Print ISSN: 0177-5103; Online ISSN: 1616-1580 Copyright © 2011 Inter-Research.
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