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A new diterpenoid from Salvia adenophora Fernald (Lamiaceae)

2012; Thieme Medical Publishers (Germany); Volume: 78; Issue: 11 Linguagem: Inglês

10.1055/s-0032-1321042

1439-0221

Angela Bisio, Gianluca Damonte, Emanuela Giacomelli, Giacomo Mele, Aldo Profumo, Giovanni Romussi, N. De Tommasi,

Essential Oils and Antimicrobial Activity

The surface exudate obtained by rinsing the aerial parts of Salvia adenophora with CH2Cl2 was subjected to repeated column chromatography on Sephadex LH-20 and silica gel and to HPLC-MS followed by semi-preparative RP-HPLC. Some known diterpenes have been isolated together with a new clerodane diterpenoid 1, identified by IR, NMR, including TOCSY, COSY, HSQC, HMBC and ROESY experiments, ESI-TRAP-MS and HR-MS analysis.