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Lopinavir/ritonavir + tenofovir Dual Therapy versus Lopinavir/ritonavir-Based Triple Therapy in HIV-Infected Antiretroviral Naïve Subjects: The Kalead Study

2010; OMICS Publishing Group; Volume: 02; Issue: 04 Linguagem: Inglês

10.4172/jaa.1000024

1948-5964

Mari Pinola, Adriano Lazzarin, Andrea Antinori, Giampiero Carosi, Giovanni Di Perri,

HIV/AIDS Research and Interventions

Subjects were recruited from 16 clinics in Italy.Inclusion criteria included HIV-1 infection diagnosis, age ≥ 18 years, no previous ARV therapy, HIV-1 RNA >400 copies/mL, and need to start cART in accordance with existing treatment guidelines and treating physician recommendation.Exclusion criteria included acute illness, history of psychiatric illness, medications incompatible with study drugs, acute HIV seroconversion, pregnancy, breast-feeding, recent substance abuse history, and selected hematology or blood chemistry abnormalities.