Artigo Acesso aberto Revisado por pares

Coronary thrombus in 34-year-old female patient with 4G/4G polymorphism in the PAI-1 gene

2016; Medknow; Volume: 2; Issue: 2 Linguagem: Inglês

10.1016/j.ijcac.2016.03.002

ISSN

2405-819X

Autores

Sinan Varol, Muhsin Kalyoncuoğlu, Burak Ayça, İrfan Şahin, Gökmen Kum, Sevgi Özcan, Ertuğrul Okuyan,

Tópico(s)

Blood properties and coagulation

Resumo

Abstract Genetic factors and hypofibrinolytic state may contribute to the likelihood of developing in myocardial infarction (MI) in young women rather than traditional risk factors. High plasminogen-activator inhibitor-1 ( PAI-1 ) level and PAI-1 gene polymorphism have been shown to be associated with thrombotic events such as myocardial infarction, deep venous thrombosis, and stroke. We determined 4G / 4G polymorphism in a 34-year-old female patient with subacute anterior myocardial infarction and coronary thrombus in left anterior descending artery on coronary angiogram.

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