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Effect of Intravenous Albumin on Renal Impairment and Mortality in Patients with Cirrhosis and Spontaneous Bacterial Peritonitis

1999; Massachusetts Medical Society; Volume: 341; Issue: 6 Linguagem: Inglês

10.1056/nejm199908053410603

1533-4406

Pau Sort, Miquel Navasa, Vicente Arroyo, Xavier Aldeguer, Ramón Planas, Luís Ruíz-del-Árbol, Lluı́s Castells, Vı́ctor Vargas, Germán Soriano, Mónica Guevara, Pere Ginés, Joan Rodés,

Organ Transplantation Techniques and Outcomes

In patients with cirrhosis and spontaneous bacterial peritonitis, renal function frequently becomes impaired. This impairment is probably related to a reduction in effective arterial blood volume and is associated with a high mortality rate. We conducted a study to determine whether plasma volume expansion with intravenous albumin prevents renal impairment and reduces mortality in these patients.