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Humoral Immunity in the healthy population of the central region of Cuba

2013; Frontiers Media; Volume: 4; Linguagem: Inglês

10.3389/conf.fimmu.2013.02.00176

1664-3224

Bequer Mendoza Leticia, G�mez Hern�ndez Tahiry, Salazar Torres Lay, Heredia Ruiz Danay, Hern�ndez Moreno Vicente, P�rez De Alejo Rodr�guez Lutgarda,

Respiratory and Cough-Related Research

Event Abstract Back to Event Humoral Immunity in the healthy population of the central region of Cuba Leticia C. Bequer Mendoza1*, Tahiry Gómez Hernández1, Lay Salazar Torres1, Danay Heredia Ruiz1, Vicente Hernández Moreno1 and Lutgarda Pérez De Alejo Rodríguez2 1 Universidad de Ciencias Médicas de Villa Clara, Unidad de Investigaciones Biomédicas, Cuba 2 Hospital Universitario "Arnaldo Milián Castro", Laboratorio Clínico, Cuba BACKGROUND: In order to study the humoral immune response in healthy population of the central region of Cuba we establish reference values of immunoglobulins IgG, IgM and IgA and C3 and C4 complement proteins in three different and interesting moments in life from the immunological point of view (birth, childhood and adulthood) in apparently healthy population of the province of Villa Clara, Cuba. METHODS: With serum samples from 200 individuals were formed 3 study groups comprised 80 new born, 60 children and 60 adults. In each case were 50% female and 50% male. Using nonparametric tests found no significant differences between gender at each group was taken as a single sample. The values of reference were established for the immunological parameters according to age, taking the central interval (95%) delimited by the 2.5th and 97.5. RESULTS: It was observed that new born had lower serum complement proteins, while children showed slightly higher serum concentrations than adults. The immunoglobulins were significantly different in each study group. CONCLUSIONS: Until the end of this work do not exist similar studies in the region that also characterize the humoral immunity, provide reference values to facilitate further studies to make decisions about possible prognoses and treatments of patients exhibiting inmunological symptoms. Keywords: Immunoglobulins, humoral immunity, Reference Values, serum complement proteins, healthy population Conference: 15th International Congress of Immunology (ICI), Milan, Italy, 22 Aug - 27 Aug, 2013. Presentation Type: Abstract Topic: Innate immunity Citation: Bequer Mendoza LC, Gómez Hernández T, Salazar Torres L, Heredia Ruiz D, Hernández Moreno V and Pérez De Alejo Rodríguez L (2013). Humoral Immunity in the healthy population of the central region of Cuba. Front. Immunol. Conference Abstract: 15th International Congress of Immunology (ICI). doi: 10.3389/conf.fimmu.2013.02.00176 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers' terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 11 Mar 2013; Published Online: 22 Aug 2013. * Correspondence: Prof. Leticia C Bequer Mendoza, Universidad de Ciencias Médicas de Villa Clara, Unidad de Investigaciones Biomédicas, Santa Clara, Cuba, ching@uclv.edu.cu Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Leticia C Bequer Mendoza Tahiry Gómez Hernández Lay Salazar Torres Danay Heredia Ruiz Vicente Hernández Moreno Lutgarda Pérez De Alejo Rodríguez Google Leticia C Bequer Mendoza Tahiry Gómez Hernández Lay Salazar Torres Danay Heredia Ruiz Vicente Hernández Moreno Lutgarda Pérez De Alejo Rodríguez Google Scholar Leticia C Bequer Mendoza Tahiry Gómez Hernández Lay Salazar Torres Danay Heredia Ruiz Vicente Hernández Moreno Lutgarda Pérez De Alejo Rodríguez PubMed Leticia C Bequer Mendoza Tahiry Gómez Hernández Lay Salazar Torres Danay Heredia Ruiz Vicente Hernández Moreno Lutgarda Pérez De Alejo Rodríguez Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.