Preparation of calcium lactobionate and lactobionic delta-lactone
1933; Volume: 11; Issue: 5 Linguagem: Inglês
10.6028/jres.011.048
ISSN2376-9815
Autores Tópico(s)Digestive system and related health
Resumo_ Crystalline lactobionic 5-lactone was obtained by dehydrating aqueous lactobionic acid by distillation with dioxane.This process is applicable for preparing lactones of other sugar acids.Lactobionic 5-lactone is a new substance of particular importance for investigations in the carbohydrate field.It is more soluble than gluconic 5-lactone, but it is not deliquescent and has a sweet taste.It melts at 195°-196°C ; in 5 percent water solution it gives [a] 2 D = +54°initially, decreasing in several hours to +22°.These values agree with the rotations of the product obtained by the oxidation of lactose with bromine water in the presence of barium carbonate.Calcium lactobionate was prepared in the crystalline state.It separates in hairlike crystals which form gelatinous mixtures with the mother liquor from which it is difficult to separate the pure substance.Consequently the crystalline salt is not suitable for the purification of lactobionic acid. CONTENTSPage I. Calcium lactobionate 713 1. Preparation of calcium lactobionate-calcium chloride 714 2. Preparation of crystalline calcium lactobionate 715 II.Lactobionic 5-lactone 716 1. Preparation of crystalline lactobionic 5-lactone
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