Portal de Periódicos da CAPES

Do molecular assays for assessing the sentinel node (SN) result in upstaging breast cancer?

2013; Elsevier BV; Volume: 39; Issue: 5 Linguagem: Inglês

10.1016/j.ejso.2013.01.134

1532-2157

Ardalan Zolnourian, Donna Appleton, Mahmood Dakka, Ferdinand Daley-Morris, Adrian Smith, Michael A. Parkes, Simon Harries, Lucie Jones, Dayalan Clarke,

Molecular Biology Techniques and Applications

Introduction: Polymerase Chain Reaction (PCR) based assays are becoming a popular option for assessing the sentinel node intra-operatively for women with breast cancer. One of the concerns with these molecular assays is that they are more sensitive than conventional H&E assessments and hence result in upstaging of disease, specifically with reference to micrometastatic disease.