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Serologic Assessment of Possibility for MERS-CoV Infection in Equids

2014; Centers for Disease Control and Prevention; Volume: 21; Issue: 1 Linguagem: Inglês

10.3201/eid2101.141342

1080-6059

Benjamin Meyer, Ignacio García‐Bocanegra, U. Wernery, Renate Wernery, Andrea Sieberg, Marcel A. Müller, Jan Felix Drexler, Christian Drosten, Isabella Eckerle,

COVID-19 epidemiological studies

In 2012, a novel coronavirus termed Middle East respiratory syndrome coronavirus (MERS-CoV) emerged on the Arabian Peninsula; the virus has been responsible for >800 human cases.Recently, evidence of MERS-CoV infection in dromedaries was obtained from the Canary Islands, the Arabian Peninsula, and Africa (1-3).Viral sequences from dromedaries and from humans infected with MERS-CoV were highly similar, suggesting a prominent role of dromedaries as an animal reservoir of the virus (4).However, the serologic assessment of other animal species has been incomplete.Investigations of domestic animal species have been restricted to goats, sheep, and cattle (3) and a limited study of horses (n = 3) (5).No evidence of recent infection was found in either study.Whereas most known CoVs have a highly restricted host range in vitro and in vivo, MERS-CoV has been found to infect a broad range of cell cultures derived from Old and New World camelids as well as humans, primates, Autochthonous Dengue Fever Imported to England from Japan, 2014