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Changes of FASH ultrasound findings in TB-HIV patients during anti-tuberculosis treatment

2014; International Union Against Tuberculosis and Lung Disease; Volume: 18; Issue: 7 Linguagem: Inglês

10.5588/ijtld.13.0029

1815-8439

Tom Heller, Claudia Wallrauch, Enrico Brunetti, Maria Teresa Giordani,

Orthopedic Infections and Treatments

Ultrasound findings of extra-pulmonary tuberculosis (TB) have been well-described, particularly in human immunodeficiency virus (HIV) co-infected patients, and are often used as a basis of diagnosis in high-prevalence settings. Changes in findings during anti-tuberculosis treatment are less well documented. We present a single-centre case series of 21 TB-HIV co-infected individuals with typical ultrasound findings present at baseline. In 16/21 (76%) patients, all findings had resolved by month 3 of treatment. In patients with persistent ultrasound findings at 3 months, non-adherence, drug resistance, chronic disease, immune-reconstitution inflammatory syndrome and alternative diagnoses were identified. Follow-up ultrasound at month 3 may help identify high-risk cases.