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Dural amyloidoma

2016; Lippincott Williams & Wilkins; Volume: 86; Issue: 13 Linguagem: Inglês

10.1212/wnl.0000000000002520

1526-632X

Simone Shibao, Fábio Augusto Ribeiro Dalprá, Celi Santos Andrade, Cláudia da Costa Leite,

Chromatin Remodeling and Cancer

A 46-year-old previously healthy woman presented with recurring left frontal and occipital headache. A brain MRI demonstrated diffuse dural thickening (figure 1, top). CSF analysis showed no abnormalities. A meningeal biopsy had pathology typical of an amyloid tumor (figure 2). Further investigations did not reveal evidence of plasma-cell tumor, multiple myeloma, systemic amyloidosis, underlying inflammatory disorder, or malignancy. Follow-up brain MRIs revealed regression of the pachymeningeal disease after treatment with corticosteroids and radiotherapy (figure 1, bottom).