Artigo Revisado por pares

Aerobic Transition-Metal-Free Visible-Light Photoredox Indole C-3 Formylation Reaction

2014; American Chemical Society; Volume: 4; Issue: 6 Linguagem: Inglês

10.1021/cs5005129

ISSN

2155-5435

Autores

Xiang Li, Xiangyong Gu, Yongjuan Li, Pixu Li,

Tópico(s)

Oxidative Organic Chemistry Reactions

Resumo

An aerobic visible-light-promoted indole C-3 formylation reaction catalyzed by Rose Bengal has been developed. This transition-metal-free process employs molecular oxygen as the terminal oxidant and uses TMEDA as the one-carbon source through C–N bond cleavage. The reaction is compatible with a variety of functional groups.

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