Artigo Revisado por pares

Ligand-Free Ni-Catalyzed Reductive Cleavage of Inert Carbon–Sulfur Bonds

2012; American Chemical Society; Volume: 14; Issue: 3 Linguagem: Inglês

10.1021/ol2033306

ISSN

1523-7060

Autores

Nekane Barbero, Rubén Martı́n,

Tópico(s)

Catalytic Cross-Coupling Reactions

Resumo

A catalytic reductive cleavage of C(sp2)– and C(sp3)–SMe bonds under ligandless conditions is presented. The method is characterized by its wide scope and high chemoselectivity profile including challenging substrate combinations, allowing the design of orthogonal and site-selectivity approaches.

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