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BIBTEX RIS

Leishmania infantum Genetic Diversity and Lutzomyia longipalpis Mitochondrial Haplotypes in Brazil

2016; Hindawi Publishing Corporation; Volume: 2016; Linguagem: Inglês

10.1155/2016/9249217

2314-6141

Paulo Eduardo Martins Ribolla, Letícia Tsieme Gushi, Maria do Socorro Pires e Cruz, Carlos Henrique Nery Costa, Dorcas Lamounier Costa, Manoel Sebastião da Costa Lima, Maria Elizabeth Moraes Cavalheiros Dorval, Alessandra Gutierrez de Oliveira, Mirella Ferreira da Cunha Santos, Vera Lucia Fonseca de Camargo-Neves, Carlos Magno Castelo Branco Fortaleza, Diego Peres Alonso,

Parasites and Host Interactions

Leishmania infantum is the etiological agent of visceral leishmaniasis (VL) in the Americas with domestic dogs being its major reservoir hosts. The main VL vector is the sandfly Lutzomyia longipalpis , while other Lutzomyia species may play a role in disease transmission. Although the genetic structure of L. infantum populations has been widely evaluated, only a few studies have addressed this subject coupled to the genetic structure of the respective sandfly vectors. In this study, we analyzed the population structure of L. infantum in three major VL endemic areas in Brazil and associated it with Lutzomyia longipalpis geographic structure.