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Extraovarian Granulosa Cell Tumor of Fallopian Tube: A Case Report

2013; Elsevier BV; Volume: 20; Issue: 6 Linguagem: Inglês

10.1016/j.jmig.2013.08.536

1553-4669

Lyliana Coutinho Resende Barbosa, F.S.M. Campos, Silvânia de Cássia Vieira Archângelo, A.M.C. Francisco,

Uterine Myomas and Treatments

Report a case of tubal tumor. Clinical case description. Minimally Invasive Surgery sector of Gynecology and Obstetrics Service of Universidade do Vale do Sapucai - UNIVAS. Pouso Alegre - MG - Brazil. A 62 years old patient, 1G1PN, menopausal for 11 years without HT use, presented with back pain. Sonography of the abdome showed complex cyst in the left ovarian. On investigation, tumor markers (CA 125, CEA) were asked with negative results. She was submitted to laparoscopy and was evidenced a mass with about 6 cm, vascularized, originated from the distal portion of the left fallopian tube. Performed resection of the mass, subjected to frozen biopsy showing malignant neoplastic cells, performed complete staging of ovarian tumor. All material was sent to anatomicopathological study. The result of immunohistochemical study (picture A) showed tubal granulose cell tumor (GCT). The expression of alpha-inhibin (picture B) and calretinin (picture C),in this morphological context, confirms GRANULOSA CELL TUMOR FROM THE ADULT TYPE. Uterus, both ovaries and the opposite tube, with no signs of malignancy. GCT are the malignant sex cord-stromal tumors of the ovary. They constitute 1-2% of all ovarian tumors. Rarely GCT can develop at an extraovarian site, but they can arise in locations other than the ovary and may be derived from the mesenchyme of the genital ridge. GCTs vary in their gross appearance. Most are partly cystic and partly solid. The case is reported for its rarity and to describe its relevance to the histologic origin and in clinical practice. Diagnosis is made by characteristic histologic features and by excluding previous GCT of ovary. Immunostains help to differentiate GCTs from other neoplasms.