Portal de Periódicos da CAPES

Computed Tomography (CT) of the Chest at Less Than 1 mSv

2014; Lippincott Williams & Wilkins; Volume: 38; Issue: 4 Linguagem: Inglês

10.1097/rct.0000000000000087

1532-3145

Ranish Deedar Ali Khawaja, Sarabjeet Singh, Matthew D. Gilman, Amita Sharma, Synho Do, Sarvenaz Pourjabbar, Atul Padole, Diego Lira, Kevin M. Brown, Jo-Anne O. Shepard, Mannudeep K. Kalra,

Medical Imaging Techniques and Applications

Purpose To assess lesion detection and diagnostic confidence of computed tomography (CT) of the chest performed at less than 1 mSv with 2 iterative reconstruction (IR) techniques. Materials and Methods Ten patients gave written informed consent for the acquisitions of images at submillisievert dose (0.9 mSv), in addition to clinical standard-dose (SD) chest CT (2.9 mSv). Submillisievert images were reconstructed with iDose4 and iterative model reconstruction (IMR). Two radiologists assessed lesion detection, margins, diagnostic confidence, and visibility of small structures. Objective noise and noise spectral density were measured. Results Lesion detection was identical for standard-dose filtered back projection (FBP), submSv iDose4, and submSv IMR. Lesion margins were better seen for 30% of detected lung lesions with submSv IMR compared to standard-dose FBP and submSv iDose4 (P < 0.05). Visibility of abdominal structures, and diagnostic confidence with submSv iDose4 and submSv IMR were similar to standard-dose FBP. There was 21% to 64% noise reduction with submSv IMR and 1% to 15% higher noise with iDose4 compared to standard-dose FBP (P < 0.0001). Conclusions Submillisievert IMR improves delineation of lesion margins compared to standard-dose FBP and submSv iDose4.