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A new mast cell degranulating peptide, granuliberin-R, in the frog (Rana rugosa) skin.

1977; Pharmaceutical Society of Japan; Volume: 25; Issue: 9 Linguagem: Inglês

10.1248/cpb.25.2464

1347-5223

Terumi Nakajima, Tadashi Yasuhara,

RNA Interference and Gene Delivery

A new mast cell degranulating peptide was isolated from the frog skin. The peptide possesses a notable sequence, in which hydrophobic amino acid residues are in the N-terminal, and hydrophilic and basic amino acid residues in the C-terminal region. Granuliberin-R belongs to a new family of the active peptides in the amphibian skin.