Portal de Periódicos da CAPES

Gender differences in cerebellar metabolism: test-retest reproducibility

1997; American Psychiatric Association; Volume: 154; Issue: 1 Linguagem: Inglês

10.1176/ajp.154.1.119

1535-7228

Nora D. Volkow, G J Wang, J S Fowler, R. Hitzemann, N. Pappas, Kathy Pascani, Christopher Wong,

Mitochondrial Function and Pathology

Back to table of contents Previous article Next article Full AccessGender differences in cerebellar metabolism: test-retest reproducibilityPublished Online:1 Apr 2006https://doi.org/10.1176/ajp.154.1.119AboutSectionsView articleAbstractPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack Citations ShareShare onFacebookTwitterLinked InEmail View articleAbstractOBJECTIVE: The purpose of this study was to evaluate gender differences in baseline measures of regional brain metabolism and to assess their reproducibility. METHOD: Fifteen male and 13 female healthy subjects, whose mean age was 44 years, were tested with positron emission tomography and [18F]fluorodeoxyglucose (FDG) under resting conditions; eight of the men and 11 of the women underwent a second FDG scan under the same conditions 4-6 weeks later to assess the reproducibility of the previous results. RESULTS: There were no differences in whole brain metabolism between the women and the men. In the first evaluation the female subjects showed significantly higher metabolism in the temporal poles and cerebellum than the male subjects. During the second evaluation the female subjects had significantly higher metabolism only in the cerebellum. CONCLUSIONS: This study documents significant and reproducible gender differences in cerebellar metabolism; their functional significance merits further evaluation. FiguresReferencesCited byDetailsCited ByQuantitative but Not Qualitative Performance Changes in Predictive Motor Timing as a Result of Overtraining2 January 2020 | The Cerebellum, Vol. 19, No. 2Relative Cerebellum Size Is Not Sexually Dimorphic across Primates13 August 2020 | Brain, Behavior and Evolution, Vol. 95, No. 2Journal of Magnetic Resonance Imaging, Vol. 50, No. 2Molecular Imaging and Biology, Vol. 21, No. 2Effects of lorazepam on saccadic eye movements: the role of sex, task characteristics and baseline traits21 May 2018 | Journal of Psychopharmacology, Vol. 32, No. 6Gender Effects On Prefrontal Cortex Oxygenation Levels During Auditory Oddball Task In ChildrenJournal of Intelligent Systems with ApplicationsEvaluation of metabolites extraction strategies for identifying different brain regions and their relationship with alcohol preference and gender difference using NMR metabolomicsTalanta, Vol. 179Behavioural Brain Research, Vol. 312Behavioural Brain Research, Vol. 314Neural Plasticity, Vol. 2016PET Clinics, Vol. 9, No. 2International Journal of Geriatric Psychiatry, Vol. 27, No. 10Journal of Neuroimaging, Vol. 22, No. 1Developmental PCB exposure induces hypothyroxinemia and sex‐specific effects on cerebellum glial protein levels in rats5 August 2010 | International Journal of Developmental Neuroscience, Vol. 28, No. 7Brain Research, Vol. 1353Social Cognitive and Affective Neuroscience, Vol. 4, No. 4Biological Trace Element Research, Vol. 124, No. 1The Cerebellum, Vol. 7, No. 3The Cerebellum, Vol. 7, No. 1Psychiatry Research: Neuroimaging, Vol. 164, No. 1CNS Spectrums, Vol. 12, No. S6European Journal of Nuclear Medicine and Molecular Imaging, Vol. 32, No. 7, Vol. 148Nuclear Medicine Communications, Vol. 25, No. 10Journal of Neuroimaging, Vol. 14, No. 4Alcoholism: Clinical and Experimental Research, Vol. 27, No. 6Journal of the Neurological Sciences, Vol. 199, No. 1-2Psychiatry Research: Neuroimaging, Vol. 114, No. 1Human Brain Mapping, Vol. 9, No. 4Annals of Nuclear Medicine, Vol. 14, No. 2Gender and Age Influences on Human Brain Mu-Opioid Receptor Binding Measured by PETJon-Kar Zubieta, M.D., Ph.D., Robert F. Dannals, Ph.D., and J. James Frost, M.D., Ph.D.1 June 1999 | American Journal of Psychiatry, Vol. 156, No. 6Sex Differences in the Striatal Dopamine D2 Receptor Binding Characteristics in VivoTiina Pohjalainen, M.Sc., Juha O. Rinne, M.D., Kjell Någren, Ph.D., Erkka SyvÄlahti, M.D., and Jarmo Hietala, M.D.1 June 1998 | American Journal of Psychiatry, Vol. 155, No. 6NeuroImage, Vol. 7, No. 3The Journal of Clinical Endocrinology & Metabolism, Vol. 83, No. 12A Review of Functional Neuroimaging in Mood Disorders: Positron Emission Tomography and Depression1 June 1997 | The Canadian Journal of Psychiatry, Vol. 42, No. 5 Volume 154Issue 1 January 1997Pages 119-121 Metrics PDF download History Published online 1 April 2006 Published in print 1 January 1997