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BIBTEX RIS

Prevalence of salivary Epstein-Barr virus in potentially malignant oral disorders and oral squamous cell carcinoma

2016; Medicina Oral S.L.; Linguagem: Inglês

10.4317/medoral.20785

ISSN

1698-6946

Autores

Leticia Bagán, MD Ocete-Monchon, Manuel Leopoldo‐Rodado, J Murillo‐Cortés, José María Díaz Fernández, Ramón Medina-González, Concepción Gimeno-Cardona, José Vicente Bagán Sebastián,

Tópico(s)

Parvovirus B19 Infection Studies

Resumo

Background: To analyze the presence of salivary Epstein-Barr virus (EBV) DNA in oral squamous cell carcinoma and potentially malignant oral disorders.Material and Methods: Three groups were studied: Group 1 (12 oral squamous cell carcinomas (OSCC)), Group 2 (12 potentially malignant oral disorders (PMD)) and Group 3 (47 healthy controls).EBV DNA salivary analysis was performed by PCR.Results: The highest percentage of positive salivary EBV DNA corresponded to the OSCC group (58.3%), followed by the PMD group (41.7%) and the controls (40.4%).The differences between groups were not statistically significant, however (p>0.05).Conclusions: Salivary EBV DNA was more prevalent in OSCC than in PMD or the controls.

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