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Anti-N-methyl-D-aspartate Receptor Encephalitis with Positive Serum Antithyroid Antibodies, IgM Antibodies Against Mycoplasma pneumoniae and Human Herpesvirus 7 PCR in the CSF

2014; Lippincott Williams & Wilkins; Volume: 33; Issue: 8 Linguagem: Inglês

10.1097/inf.0000000000000408

1532-0987

Paulo Venâncio, Maria João Brito, Gabriela Pereira, José Pedro Vieira,

Cytomegalovirus and herpesvirus research

We report the case of a boy with an encephalopathy associated with extrapyramidal and psychiatric symptoms and anti-N-methyl-D-aspartate receptor antibodies. He had positive serum antithyroid antibodies, IgM antibodies against Mycoplasma pneumoniae and human herpesvirus 7 polymerase chain reaction in the cerebrospinal fluid. He was successfully treated with rituximab, after steroids, intravenous immunoglobulin and plasma exchange. The pathophysiology of this disorder may be post-infectious and autoimmune.