Inflammation and Vascular Injury
2012; Volume: 12; Issue: 3 Linguagem: Inglês
10.1177/155989771203015
ISSN2155-756X
Autores Tópico(s)Cell Adhesion Molecules Research
ResumoThe focus this article is on a class of leukocyte adhesion molecules, leukocyte β2-integrins, among which Mac-1 (aMb2, CD11b/CD18) is the most common integrin on neutrophils. The leukocyte Mac-1 receptor interacts with the glyocoprotein Iba (GPIba) receptor on platelets, thereby regulating pro-inflammatory and pro-thrombotic bidirectional signals in both inflammatory cells and platelets.
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