Portal de Periódicos da CAPES

Etiology of Exudative Diathesis, Encephalomalacia, and Muscular Degeneration in the Chicken

1962; Elsevier BV; Volume: 41; Issue: 2 Linguagem: Inglês

10.3382/ps.0410473

1525-3171

L.J. Machlin, Rebecca Gordon,

Selenium in Biological Systems

IN THE young chicken a dietary deficiency of vitamin E will result in either encephalomalacia, exudative diathesis, muscular degeneration or some combination of these symptoms. While the gross effects and histopathology involved in these disorders have been described (Pappenheimer and Goettsch, 1931; Jungherr et al., 1956; Coggeshall and Bieri, 1960; Dam and Glavind, 1938; Dam et al., 1952; Machlin and Shalkop, 1956), complete understanding of the nutritional factors other than vitamin E deficiency which determined the appearance of the various symptoms has not been achieved (Ames, 1956). Accordingly it has been difficult to produce one E-deficiency symptom uncomplicated by the presence of another. Recently several major observations have clarified the factors involved, namely that; selenium protects chickens against exudative diathesis (Patterson et al., 1957; Schwarz et al., 1957) but not against encephalomalacia (Dam et al., 1957; Ames and Swanson, 1958); dietary linoleic or arachidonic acid is necessary for the …