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Occurrence of Gastric Cancer among Patients with Pernicious Anemia at the Boston City Hospital

1955; Massachusetts Medical Society; Volume: 252; Issue: 26 Linguagem: Inglês

10.1056/nejm195506302522601

1533-4406

Norman Zamchegk, Ernest Grable, Allyn B. Ley, Leona Norman,

Helicobacter pylori-related gastroenterology studies

ALTHOUGH it is generally recognized that gastric cancer occurs with increased frequency in patients with pernicious anemia,1 2 3 reported rates vary widely from a low of 0.16 per cent4 to a high of 14.9 per cent.5 Differences in the sampling methods, the relatively small number of patients with pernicious anemia available at any one clinic and the differing criteria utilized for the diagnosis of pernicious anemia contribute to the disparity among these figures. Many patients with pernicious anemia are seen at the Boston City Hospital every year. To assess the practicality of routine screening of these patients for gastric cancer it . . .