Portal de Periódicos da CAPES

Remarkable Improvement Achieved by Imidazole Derivatives in Ruthenium-Catalyzed Hydroesterification of Alkenes Using Formates

2012; American Chemical Society; Volume: 14; Issue: 18 Linguagem: Inglês

10.1021/ol301850y

1523-7060

Hideyuki Konishi, Tsuyoshi Ueda, Takashi Muto, Kei Manabe,

Organometallic Complex Synthesis and Catalysis

Imidazole derivatives are revealed to be effective ligands in the Ru-catalyzed hydroesterification of alkenes using formates, affording one-carbon-elongated esters in high yields. Further, intramolecular hydroesterification was successfully performed to give lactones for the first time. Imidazole derivatives can contribute to promote the reaction as well as to suppress the undesired decarbonylation of formate. Toxic CO gas, a directing group, and large excess alkenes are not required.