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Studies on the constituents of Solanum plants. V. The constituents of S. lyratum Thunb. II.

1985; Pharmaceutical Society of Japan; Volume: 33; Issue: 1 Linguagem: Inglês

10.1248/cpb.33.67

1347-5223

Kōtarō Murakami, HISATAKA EZIMA, Yoshihisa Takaishi, Yoshio Takeda, Tetsuro Fujita, AKIHIKO SATO, Yoko Nagayama, Toshihiro Nohara,

Potato Plant Research

Two new steroidal alkaloid glycosides, tentatively named SL-c (1) and SL-d (2), were obtained from the stems of Solanum lyratum THUNB. The chemical structures of 1 and 2 were characterized respectively as β-lycotrioside and β-lycotetraoside, both having a mixture of (25ζ)-solanidan-3β, 23β-diol and (25ζ)-Δ5-solaniden-3β, 23β-diol as the aglycone moiety. These compounds markedly inhibited the growth of a human cervical cancer cell line, JTC-26.