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Pilot Study of Detection, Radiologist Confidence and Image Quality With Sinogram-Affirmed Iterative Reconstruction at Half–Routine Dose Level

2013; Lippincott Williams & Wilkins; Volume: 37; Issue: 2 Linguagem: Inglês

10.1097/rct.0b013e31827e0e93

1532-3145

Joel G. Fletcher, W. Krueger, David M. Hough, James E. Huprich, Jeff L. Fidler, Jia Wang, Maria M. Shiung, William S. Harmsen, Katharine L. Grant, Cynthia H. McCollough,

Advanced X-ray and CT Imaging

Objective The objective of this study was to determine the effect of Sinogram-Affirmed Iterative Reconstruction (SAFIRE) on radiological detection, diagnostic confidence, and image quality at half-dose, contrast-enhanced abdominopelvic computed tomography. Methods Forty dual-source examinations were reconstructed using routine-dose with filtered back projection, half-dose filtered back projection, and half-dose SAFIRE. Three radiologists detected lesions in abdominopelvic organs, reporting findings of potential medical significance, diagnostic confidence, and image quality. Results There was greater than 78% concordance between full- and half-dose images ± SAFIRE, and no difference in the detection of lesions within organs between half-dose images ± SAFIRE (P = 0.22 – 1.0). Detection of potentially important findings varied by reader, but not between dose/reconstruction methods. Diagnostic confidence varied widely (P < 0.001 to P > 0.91). Sinogram-Affirmed Iterative Reconstruction significantly improved image quality in the pelvis (P ≤ 0.04). Conclusions Half-dose images ± SAFIRE had organ-specific detections similar to routine-dose images. Sinogram-Affirmed Iterative Reconstruction improved image quality in the pelvis, but diagnostic confidence and image quality scores in the abdomen depended on the reader.