Carta Revisado por pares

Mutations in the β‐globin gene from a Saudi population: an update

2016; Wiley; Volume: 38; Issue: 2 Linguagem: Inglês

10.1111/ijlh.12463

ISSN

1751-553X

Autores

J. Francis Borgio, Sayed AbdulAzeez, Zaki A. Naserullah, Sana Al‐Jarrash, Rudaynah A. Alali, Mohammed Al-Madan, Fahd A Al-Muhanna, Ahmed Alsuliman, AwatifM Al-Nafie, Martin H. Steinberg, Amein K. Al‐Ali,

Tópico(s)

Epigenetics and DNA Methylation

Resumo

International Journal of Laboratory HematologyVolume 38, Issue 2 p. e38-e40 Letter to the Editor Mutations in the β-globin gene from a Saudi population: an update J. F. Borgio, J. F. Borgio [email protected] [email protected] orcid.org/0000-0001-7199-1540 Institute for Research & Medical Consultation, University of Dammam, Dammam, Saudi ArabiaSearch for more papers by this authorS. AbdulAzeez, S. AbdulAzeez Institute for Research & Medical Consultation, University of Dammam, Dammam, Saudi ArabiaSearch for more papers by this authorZ. A. Naserullah, Z. A. Naserullah Dammam Maternity and Child Hospital, Dammam, Saudi ArabiaSearch for more papers by this authorS. Al-Jarrash, S. Al-Jarrash Dammam Maternity and Child Hospital, Dammam, Saudi ArabiaSearch for more papers by this authorR. A. Al-Ali, R. A. Al-Ali King Fahd Hospital of the University, University of Dammam, Al-Khobar, Saudi ArabiaSearch for more papers by this authorM. S. Al-Madan, M. S. Al-Madan King Fahd Hospital of the University, University of Dammam, Al-Khobar, Saudi ArabiaSearch for more papers by this authorF. Al-Muhanna, F. Al-Muhanna King Fahd Hospital of the University, University of Dammam, Al-Khobar, Saudi ArabiaSearch for more papers by this authorA. M. Al-Suliman, A. M. Al-Suliman King Fahd Hospital, King Faisal University, Al-Ahssa, Saudi ArabiaSearch for more papers by this authorA. Al-Nafie, A. Al-Nafie King Fahd Hospital of the University, University of Dammam, Al-Khobar, Saudi ArabiaSearch for more papers by this authorM. H. Steinberg, M. H. Steinberg Centre of Excellence in Sickle Cell Disease, Boston University School of Medicine, Boston, MA, USASearch for more papers by this authorA. K. Al-Ali, A. K. Al-Ali Institute for Research & Medical Consultation, University of Dammam, Dammam, Saudi Arabia King Fahd Hospital, King Faisal University, Al-Ahssa, Saudi ArabiaSearch for more papers by this author J. F. Borgio, J. F. Borgio [email protected] [email protected] orcid.org/0000-0001-7199-1540 Institute for Research & Medical Consultation, University of Dammam, Dammam, Saudi ArabiaSearch for more papers by this authorS. AbdulAzeez, S. AbdulAzeez Institute for Research & Medical Consultation, University of Dammam, Dammam, Saudi ArabiaSearch for more papers by this authorZ. A. Naserullah, Z. A. Naserullah Dammam Maternity and Child Hospital, Dammam, Saudi ArabiaSearch for more papers by this authorS. Al-Jarrash, S. Al-Jarrash Dammam Maternity and Child Hospital, Dammam, Saudi ArabiaSearch for more papers by this authorR. A. Al-Ali, R. A. Al-Ali King Fahd Hospital of the University, University of Dammam, Al-Khobar, Saudi ArabiaSearch for more papers by this authorM. S. Al-Madan, M. S. Al-Madan King Fahd Hospital of the University, University of Dammam, Al-Khobar, Saudi ArabiaSearch for more papers by this authorF. Al-Muhanna, F. Al-Muhanna King Fahd Hospital of the University, University of Dammam, Al-Khobar, Saudi ArabiaSearch for more papers by this authorA. M. Al-Suliman, A. M. Al-Suliman King Fahd Hospital, King Faisal University, Al-Ahssa, Saudi ArabiaSearch for more papers by this authorA. Al-Nafie, A. Al-Nafie King Fahd Hospital of the University, University of Dammam, Al-Khobar, Saudi ArabiaSearch for more papers by this authorM. H. Steinberg, M. H. Steinberg Centre of Excellence in Sickle Cell Disease, Boston University School of Medicine, Boston, MA, USASearch for more papers by this authorA. K. Al-Ali, A. K. Al-Ali Institute for Research & Medical Consultation, University of Dammam, Dammam, Saudi Arabia King Fahd Hospital, King Faisal University, Al-Ahssa, Saudi ArabiaSearch for more papers by this author First published: 29 January 2016 https://doi.org/10.1111/ijlh.12463Citations: 7Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat No abstract is available for this article. References 1Al-Sultan A, Phanasgaonkar S, Suliman A, Al-Baqushi M, Nasrullah Z, Al-Ali A. Spectrum of β-thalassemia mutations in the Eastern Province of Saudi Arabia. Hemoglobin 2011; 35: 125–34. 2Al-Ali AK, Al-Ateeq S, Imamwerdi BW, Al-Sowayan S, Al-Madan M, Al-Muhanna F, Qaw F. Molecular bases of β-thalassemia in the Eastern Province of Saudi Arabia. J Biomed Biotechnol 2005; 4: 322–5. 3Borgio JF, AbdulAzeez S, Al-Nafie AN, Naserullah ZA, Al-Jarrash S, Al-Madan MS, Al-Ali AK. A novel HBA2 gene conversion in cis or trans: “α12 allele” in a Saudi population. Blood Cells Mol Dis 2014; 53: 199–203. 4Akhtar MS, Qaw F, Borgio JF, Albuali W, Suliman A, Nasserullah Z, Al-Ali A. Spectrum of α-thalassemia mutations in transfusion-dependent β-thalassemia patients from the Eastern Province of Saudi Arabia. Hemoglobin 2013; 37: 65–73. 5Al-Nafie AN, Borgio JF, AbdulAzeez S, Al-Suliman AM, Qaw FS, Naserullah ZA, Al-Ali AK. Co-inheritance of novel ATRX gene mutation and globin (α & β) gene mutations in transfusion dependent beta-thalassemia patients. Blood Cells Mol Dis 2015; 55: 27–9. 6Ngo DA, Steinberg MH. Genomic approaches to identifying targets for treating β hemoglobinopathies. BMC Med Genomics 2015; 8: 44. 7Zahed L. The spectrum of β-thalassemia mutations in the Arab populations. J Biomed Biotechnol 2001; 1: 129–32. 8El-Mouzan MI, Al-Salloum AA, Al-Herbish AS, Qurachi MM, Al-Omar AA. Regional variations in the prevalence of consanguinity in Saudi Arabia. Saudi Med J 2007; 28: 1881–4. 9Cürük MA, Molchanova TP, Postnikov YuV, Pobedimskaya DD, Liang R, Baysal E, Kolodey S, Smetanina NS, Tokarev YuN, Rumyantsev AG. Beta-thalassemia alleles and unstable hemoglobin types among Russian pediatric patients. Am J Hematol 1994; 46: 329–32. 10Vetter B, Schwarz C, Kohne E, Kulozik AE. Beta-thalassaemia in the immigrant and non-immigrant German populations. Br J Haematol 1997; 97: 266–72. 11Ohba Y, Hattori Y, Harano T, Harano K, Fukumaki Y, Ideguchi H. Beta-thalassemia mutations in Japanese and Koreans. Hemoglobin 1997; 21: 191–200. 12Najmabadi H, Karimi-Nejad R, Sahebjam S, Pourfarzad F, Teimourian S, Sahebjam F, Karimi-Nejad MH. The β-thalassemia mutation spectrum in the Iranian population. Hemoglobin 2001; 25: 285–96. Citing Literature Volume38, Issue2April 2016Pages e38-e40 ReferencesRelatedInformation

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