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A new alkaloid antibiotic tetrazomine structure determination.

1991; Springer Nature; Volume: 44; Issue: 12 Linguagem: Inglês

10.7164/antibiotics.44.1367

1881-1469

SUTOMU SATO, Fukushi Hirayama, Takeshi Saito, Hidetoshi Kaniwa,

Chemical synthesis and alkaloids

A new alkaloid antibiotic tetrazomine was isolated from the culture broth of Saccharothrix mutabilis subsp. chichijimaensis subsp. nov., and its structure was determined to be I by means of spectroscopic measurements. It has an unusual structure which consists of six rings, including piperidine, piperazine, oxazole, and pyrrolidine rings.