Portal de Periódicos da CAPES

Syntheses and Structural Characterization of the (OC n OPor) Capped Porphyrins: Co(OC 2 OPor)·CH 2 Cl 2 , Co(OC 2 OPor)(NO) out ·0.46CHCl 3 , Co(OC 3 OPor)·CHCl 3 , and Co(OC 3 OPor)(MeIm)·3C 7 H 8

2000; American Chemical Society; Volume: 39; Issue: 25 Linguagem: Inglês

10.1021/ic0006753

1520-510X

P.G. Jene, James A. Ibers,

Heme Oxygenase-1 and Carbon Monoxide

The compounds Co(OC2OPor)·CH2Cl2 (1), Co(OC2OPor)(NO)out·0.46CHCl3 (2), Co(OC3OPor)·CHCl3 (3), and Co(OC3OPor)(MeIm)·3C7H8 (4) (OC2OPor = 5,10,15,20-(benzene-1,2,4,5-tetrakis(2-phenyloxy)ethoxy)-2',2' ', 2' '',2' '' '-tetraylporphyrinato dianion; OC3OPor = 5,10,15,20-(benzene-1,2,4,5-tetrakis(2-phenyloxy)propoxy)-2',2' ',2' '',2' '' '-tetraylporphyrinato dianion; MeIm = 1-methylimidazole), have been synthesized, and their structures have been determined by single-crystal X-ray diffraction methods at T = −120 °C: 1, a = 8.824(1) Å, b = 16.674(1) Å, c = 16.836(1) Å, α = 104.453(1)°, β = 92.752(1)°, γ = 90.983(1)°, P1̄, Z = 2; 2, a = 9.019(1) Å, b = 16.588(2) Å, c = 16.909(2) Å, α = 103.923(2)°, β = 92.082(2)°, γ = 93.583(2)°, P1̄, Z = 2; 3, a = 13.484(3) Å, b = 14.404(3) Å, c = 14.570(3) Å, α = 105.508(3)°, β = 100.678(3)°, γ = 93.509(4)°, P1̄, Z = 2; 4, a = 16.490(1) Å, b = 22.324(2) Å, c = 17.257(1) Å, b = 92.437(1)°, P21/n, Z = 4. These compounds are the first structurally characterized Co-bound members of the OCnOPor ligand system. The NO ligand in 2 and the MeIm ligand in 4 bind asymmetrically and lead to several metrical changes in these porphyrins, e.g., variations in average porphryin deviations and Co atom displacements relative to the porphyrinato N atoms and the mean porphyrin planes.