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Adrenocortical Function in Anorexia Nervosa before and after Lobotomy

1953; Massachusetts Medical Society; Volume: 248; Issue: 19 Linguagem: Inglês

10.1056/nejm195305072481904

1533-4406

Mark D. Altschule,

Virus-based gene therapy research

CLINICAL differences between anorexia nervosa and panhypopituitarism are usually so striking that differentiation of these two disorders is not difficult.1 There are also important physiologic differences. Nevertheless, the idea persists in some quarters that the physical manifestations of anorexia nervosa are partly due to secondary hypoadrenalism and that ACTH (adrenocorticotrophic hormone) should have a specific, beneficial effect. Observations on adrenocortical function in anorexia nervosa made at this hospital and elsewhere may be of interest in this connection.Material and MethodsA nineteen-year-old girl with anorexia nervosa was studied at McLean Hospital; the clinical manifestations of her disorder have already been . . .